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Search Results for " (e/z)-rigosertib sodium "

3

Compounds

Cat No. Product Name Synonyms Targets
T6070 (E/Z)-Rigosertib sodium (E/Z) ON-01910 sodium PLK
ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidativ...
T5818 Rigosertib sodium Rigosertib,Estybon,ON-01910 Apoptosis , PLK , PI3K
Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.
T16750 Rigosertib ON-01910 Apoptosis , FLT , PLK , PI3K , Bcr-Abl , CDK , PDGFR , Src
Rigosertib (ON-01910) is a selective and non-ATP-competitive inhibitor of PLK1 (IC50: 9 nM). Rigosertib is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition of the PI3 kina...
TargetMol